Hotels Near
Downtown Santiago

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Featured Downtown Santiago Hotels

Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8/10 Very Good! (611 reviews)
The people are very friendly, the facilities are lovely and comfortable. It has a very interesting museum. It's well located.

Reviewed on Nov 20, 2025

Almacruz Hotel y Centro de Convenciones
Hotel HW Libertad

Hotel HW Libertad

3.5 out of 5
22 Libertad Santiago Región Metropolitana
Stay at this hotel in Santiago. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Costanera Center and Centro Cultural Matucana 100 are ...
8.6/10 Excellent! (143 reviews)
Helpful staff

Reviewed on Nov 10, 2025

Hotel HW Libertad
Hotel Casa Zañartu

Hotel Casa Zañartu

4 out of 5
Avenida Compañia de Jesus 1520 Santiago Santiago
Fully refundable
Stay at this hotel in Santiago. Enjoy free breakfast, free WiFi, and room service. Our guests praise the helpful staff in our reviews. Popular attractions Costanera ...
8.6/10 Excellent! (258 reviews)
centrally located near subway. short walk to Lastarria and many great restaurants. Nice, helpful staff. Good WiFi and areas to use computer.

Reviewed on Dec 3, 2025

Hotel Casa Zañartu
LOFT Hotel by Sommelier Hoteles

LOFT Hotel by Sommelier Hoteles

3 out of 5
264 Miraflores Santiago Santiago
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santiago. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
9/10 Wonderful! (183 reviews)
Great service, clean rooms, perfect location.

Reviewed on Dec 2, 2025

LOFT Hotel by Sommelier Hoteles
Mercure Santiago Centro

Mercure Santiago Centro

3.5 out of 5
Av. Libertador Bernardo O Higgins, 632 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
Book a stay at this business-friendly hotel in Santiago. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff in ...
8.2/10 Very Good! (999 reviews)
Clean rooms, handy location. This is a mid range hotel & for that it’s great. Rooms a bit dark (just 1 more lamp per room please!) but good breakfast & staff keen to help. Ray at front desk is a champion.

Reviewed on Nov 21, 2025

Mercure Santiago Centro
RQ Santiago

RQ Santiago

3 out of 5
Alameda 1449 Local 11 - Centro Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santiago. Enjoy free breakfast, parking (surcharge), and a 24-hour front desk. Popular attractions Costanera Center and Parque Arauco Mall ...
8.4/10 Very Good! (594 reviews)
Good value for the money

Reviewed on Dec 4, 2025

RQ Santiago
The Singular Santiago

The Singular Santiago

5 out of 5
Merced 294 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the bar and the helpful staff in our reviews. ...
9.4/10 Exceptional! (672 reviews)
The staff were wonderful and did a great job.

Reviewed on Dec 4, 2025

The Singular Santiago
Park Plaza Apart Hotel

Park Plaza Apart Hotel

3 out of 5
Av. Huerfanos 545 Santiago Region Metropolitana
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Book a stay at this business-friendly aparthotel in Santiago. Enjoy free WiFi, free parking, and a health club. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (634 reviews)
Great location with central city square within walking distance, close to metro, supermarket and park. It was quiet. Reasonably clean.

Reviewed on Dec 3, 2025

Park Plaza Apart Hotel
Luciano K Hotel

Luciano K Hotel

4.5 out of 5
Merced, 84 Santiago Región Metropolitana
Fully refundableReserve now, pay when you stay
Book a stay at this luxury hotel in Santiago. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the breakfast and the bar in our reviews. ...
8.8/10 Excellent! (681 reviews)
The hotel is located in a quiet area. There plenty of restaurants nearby and a lovely park across the street. The hotel itself is lovely, decor is really nice. The rooftop bar is great. All staff, reception, cleaners and bar staff are friendly and helpful. I really liked this hotel.

Reviewed on Dec 6, 2025

Luciano K Hotel
Hotel Cumbres Lastarria

Hotel Cumbres Lastarria

4 out of 5
Jose Victorino Lastarria 299 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
Stay at this hotel in Santiago. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (911 reviews)
Attractive hotel with great facilities and good sized rooms. Staff friendly and helpful. Would stay again. Highly recommended.

Reviewed on Dec 6, 2025

Hotel Cumbres Lastarria
Le Méridien Santiago

Le Méridien Santiago

4 out of 5
Av. Libertador Bernardo O'Higgins 136 Santiago Region Metropolitana
Fully refundableReserve now, pay when you stay
Book a stay at this ski hotel in Santiago. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Popular attractions Costanera Center and Parque Arauco ...
8.4/10 Very Good! (539 reviews)
Kudos to Hotel Meridien for having Ms Ana Echeverria and Mr John Freire. They are helpful, friendly and accommodating. A pleasure to stay here. The room is immaculate, food delicious. The Hotel close to Metro yet quiet, safe area.

Reviewed on Dec 6, 2025

Le Méridien Santiago
Hotel Sommelier Boutique

Hotel Sommelier Boutique

3.5 out of 5
Merced 433 Santiago Región Metropolitana de Santiago
Fully refundableReserve now, pay when you stay
Book a stay at this ski hotel in Santiago. Enjoy free breakfast, free WiFi, and 2 bars/lounges. Our guests praise the breakfast and the helpful staff in our ...
9/10 Wonderful! (661 reviews)
The suite was very large. They gave us an extra hour. So we didn't have to check out till 1. The rooftop bar was very nice.

Reviewed on Dec 6, 2025

Hotel Sommelier Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels in Downtown Santiago

Santiago is a city that has a lot going on, but you have your sights set on Downtown Santiago. This part of town is perfect for what you want to be doing, and that is everything that is not on everyone’s radar. For all that Downtown Santiago has going on, you’ll still need a place to crash, eventually. But you don’t want any old shack, you need something that fits the trip. We have a slew of Downtown Santiago hotels that will do the trick.

A beautiful day in the neighborhood

As much as you like getting out there, it’s also good to know a part of Santiago so well you’ll be telling the tourists where to go. Make friends with the concierge or be bold and chat up a local. It’s your trip, so choose your own adventure. And when you get in at night, you’ll have a comfy room and plenty of amenities to help you settle in. Call a friend and spin tales from the Downtown Santiago underground. What’s a journey without a good story to go with it?

Beyond the block

We’re not talking about the Downtown Santiago city block. We’re talking about looking beyond that block of hotels you always focus on. We give you tons of ways to sort our stash of Downtown Santiago cheap hotels. And if you feel like living a little, but not killing your vacation vibes, choose the Hotwire Hot Rate deal. Filter by:

  • Hotwire Hot Rate: Snag some of the best hotels in Downtown Santiago at an almost too good to be true rate. After you book, we’ll reveal the name of the hotel. You can get a luxury hotel at a budget price.
  • Price: You have a price in mind, and we have solutions. Hotels start as low as $55
  • Amenities: Rooftop lounge, designer furniture, 24-7 room service, and everything else you look for to live it up large.

Find the Downtown Santiago hotel you want, book it, and never look back. Because your great escape is ahead of you.