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Hotels in Upstate South Carolina

See all 277 Hotels in Upstate South Carolina
La Quinta Inn & Suites Greenville-Haywood

La Quinta Inn & Suites Greenville-Haywood

65 W Orchard Park Dr, Greenville
    2.5 out of 5.0
     
     

    Situated in Greenville, this hotel is within a 15-minute walk of Southern Wesleyan University Greenville Education Center, Haywood Mall, and Patewood Memorial ...

    La Quinta Inn & Suites Greenville-Haywood$93

    La Quinta Inn & Suites Greenville-Haywood$93
    The Westin Poinsett Greenville

    The Westin Poinsett Greenville

    120 South Main St, Greenville
      4.0 out of 5.0
       
       

      This family-friendly Greenville hotel is located in the business district, within a 15-minute walk of The Peace Center and Falls Park on the Reedy. Centre Stage ...

      The Westin Poinsett Greenville$189

      The Westin Poinsett Greenville$189
      Spartanburg Marriott

      Spartanburg Marriott

      299 North Church Street, Spartanburg
        3.5 out of 5.0
         
         

        Located in the heart of Spartanburg, this hotel is within a 5-minute walk of Hub City Railroad Museum and Spartanburg Memorial Auditorium. Wofford College and ...

        Spartanburg Marriott$127

        Spartanburg Marriott$127
        Best Western Greenville Airport Inn

        Best Western Greenville Airport Inn

        5009 Pelham Road, Greenville
          2.5 out of 5.0
           
           

          Situated near the airport, this hotel is within 12 mi (20 km) of TD Convention Center, Bon Secours Wellness Arena, and Greenville Zoo. The Peace Center is 10.1 ...

          Best Western Greenville Airport Inn$85

          Best Western Greenville Airport Inn$85
          Rodeway Inn Millennium

          Rodeway Inn Millennium

          2756 Laurens Rd, Greenville
            2.5 out of 5.0
             
             

            Located in the heart of Greenville, this hotel is 1 mi (1.6 km) from CU Intl. Center for Automotive Research and within 3 mi (5 km) of Gower Estates Park and ...

            Rodeway Inn Millennium$64

            Rodeway Inn Millennium$64
            Comfort Suites Greenville South

            Comfort Suites Greenville South

            10 Kalyns Way, Piedmont
              2.5 out of 5.0
               
               

              Located in the heart of Piedmont, this hotel is within 9 mi (15 km) of Lakeside Park, Falls Park on the Reedy, and The Peace Center. 7th Inning Splash Waterpark ...

              Comfort Suites Greenville South$110

              Comfort Suites Greenville South$110
              Days Inn Greenville

              Days Inn Greenville

              60 Roper Mountain Rd, Greenville
                2.0 out of 5.0
                 
                 

                Situated in Greenville, this motel is within 2 mi (3 km) of Roper Mountain Science Center, Patewood Memorial Hospital, and The Shops at Greenridge. Haywood Mall ...

                Days Inn Greenville$67

                Days Inn Greenville$67
                Comfort Inn and Suites Greenville

                Comfort Inn and Suites Greenville

                831 Congaree Rd, Greenville
                  2.0 out of 5.0
                   
                   

                  Located in the heart of Greenville, this hotel is within 1 mi (2 km) of Roper Mountain Science Center and Patewood Memorial Hospital. Haywood Mall and The Shops ...

                  Comfort Inn and Suites Greenville$89

                  Comfort Inn and Suites Greenville$89
                  Comfort Inn Haywood Mall Area

                  Comfort Inn Haywood Mall Area

                  246 Congaree Road, Greenville
                    2.5 out of 5.0
                     
                     

                    Situated in the business district, this hotel is within 1 mi (2 km) of Haywood Mall, Southern Wesleyan University Greenville Education Center, and Patewood Memorial ...

                    Comfort Inn Haywood Mall Area$87

                    Comfort Inn Haywood Mall Area$87
                    Aloft Greenville Downtown

                    Aloft Greenville Downtown

                    5 North Laurens Street, Greenville
                      3.0 out of 5.0
                       
                       

                      Located in Greenville Downtown, this hotel is within a 10-minute walk of Alchemy Comedy Theater and The Peace Center. Falls Park on the Reedy is 0.8 mi (1.2 ...

                      Aloft Greenville Downtown$144

                      Aloft Greenville Downtown$144
                      Map

                      Upstate South Carolina Hotel Guide

                      Search for hotels in Upstate South Carolina on Hotwire. Finding hotels in Upstate South Carolina using one of the methods below, is simple and quick:

                      • Look through our selection of featured hotels in Upstate South Carolina and check into the different facilities they offer
                      • Use the map to find hotels in the Upstate South Carolina areas you prefer or hotels nearest to tourist attractions you plan to visit
                      • Use the filters to see hotels in a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Upstate South Carolina
                      • Or just enter your travel dates to view the best deals on hotels in Upstate South Carolina - while they last.