Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Book with Confidence. Price Match Guarantee.

No Hotwire Cancellation Fee

We've Saved Customers over $3.1 Billion


Hotels in Southeast Minnesota

See all 181 Properties in Southeast Minnesota
Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

9 3rd Ave Nw, Rochester
    3.5 out of 5.0
     
     

    Experience the look and feel of the Kahler Inn & Suites. Every room has refrigerators, flat screen televisions, coffee makers, furniture, and more!

    Kahler Inn and Suites - Mayo Clinic Area$107

    Kahler Inn and Suites - Mayo Clinic Area$107
    Kahler Apache

    Kahler Apache

    1517 16th St Sw, Rochester
      3.0 out of 5.0
       
       

      This family-friendly Rochester hotel is located in a shopping district, within 2 mi (3 km) of Apache Mall and Plummer House. Mayo Clinic is 2.2 mi (3.6 km) ...

      Kahler Apache$76

      Kahler Apache$76
      Kahler Grand Hotel

      Kahler Grand Hotel

      20 2nd Ave Sw, Rochester
        3.0 out of 5.0
         
         

        Located in the heart of Rochester, this hotel is within 1 mi (2 km) of University of Minnesota-Rochester and Mayo Clinic. Shops University Square and Rochester ...

        Kahler Grand Hotel$45

        Kahler Grand Hotel$45
        Country Inn & Suites by Radisson, Rochester South, MN

        Country Inn & Suites by Radisson, Rochester South, MN

        77 Woodlake Drive SE, Rochester
          3.0 out of 5.0
           
           

          Located near the airport, this family-friendly hotel is within 6 mi (10 km) of Olmsted County Fairgrounds, Soldiers Field Veterans Memorial, and Mayo Civic Center. ...

          Country Inn & Suites by Radisson, Rochester South, MN$101

          Country Inn & Suites by Radisson, Rochester South, MN$101
          Best Western Rivertown Hotel & Suites

          Best Western Rivertown Hotel & Suites

          752 Withers Harbor Dr, Red Wing
            2.5 out of 5.0
             
             

            Situated in Red Wing, this hotel is within 2 mi (3 km) of Sheldon Theatre of Performing Arts, Aliveo Military Museum, and Red Wing Shoe Store & Museum. Barn ...

            Best Western Rivertown Hotel & Suites$106

            Best Western Rivertown Hotel & Suites$106
            Days Inn by Wyndham Rochester Downtown

            Days Inn by Wyndham Rochester Downtown

            6 1st Avenue Northwest, Rochester
              2.0 out of 5.0
               
               

              Situated in Rochester, this hotel is steps from University of Minnesota-Rochester and Mayo Clinic. Shops University Square and Rochester Civic Theater are also ...

              Days Inn by Wyndham Rochester Downtown$59

              Days Inn by Wyndham Rochester Downtown$59
              GuestHouse International Inn & Suites Rochester

              GuestHouse International Inn & Suites Rochester

              435 16th Ave Nw, Rochester
                2.5 out of 5.0
                 
                 

                Situated in Rochester, this motel is 0.6 mi (1 km) from Saint Marys Hospital and 1.3 mi (2.1 km) from Mayo Clinic. Assisi Heights and Plummer House are also ...

                GuestHouse International Inn & Suites Rochester$76

                GuestHouse International Inn & Suites Rochester$76
                Super 8 by Wyndham Rochester Mayo Clinic Area

                Super 8 by Wyndham Rochester Mayo Clinic Area

                106 SE 21st Street, Rochester
                  2.0 out of 5.0
                   
                   

                  Situated in Rochester, this hotel is 0.9 mi (1.4 km) from Olmsted County Fairgrounds and 2.3 mi (3.8 km) from Mayo Clinic. Soldiers Field Golf Course and Apache ...

                  Super 8 by Wyndham Rochester Mayo Clinic Area$62

                  Super 8 by Wyndham Rochester Mayo Clinic Area$62
                  Comfort Suites

                  Comfort Suites

                  4141 Maine Avenue SE, Rochester
                    2.5 out of 5.0
                     
                     

                    Situated in Rochester, this hotel is within 6 mi (10 km) of Olmsted County Fairgrounds, Mayo Clinic, and Soldiers Field Veterans Memorial. Soldiers Field Golf ...

                    Comfort Suites$97

                    Comfort Suites$97
                    AmericInn by Wyndham Rochester Airport

                    AmericInn by Wyndham Rochester Airport

                    7320 Airport View Dr Sw, Rochester
                      2.0 out of 5.0
                       
                       

                      Situated in Rochester, this hotel is within 9 mi (15 km) of Olmsted County Fairgrounds, Mayo Clinic, and Maple Valley Golf & Country Club. Soldiers Field Veterans ...

                      AmericInn by Wyndham Rochester Airport$96

                      AmericInn by Wyndham Rochester Airport$96
                      Map

                      Southeast Minnesota Hotel Guide

                      Search for hotels in Southeast Minnesota on Hotwire. Finding hotels in Southeast Minnesota using one of the methods below, is simple and quick:

                      • Look through our selection of featured hotels in Southeast Minnesota and check into the different facilities they offer
                      • Use the map to find hotels in the Southeast Minnesota areas you prefer or hotels nearest to tourist attractions you plan to visit
                      • Use the filters to see hotels in a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Southeast Minnesota
                      • Or just enter your travel dates to view the best deals on hotels in Southeast Minnesota - while they last.