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St. Charles

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St. Charles Flights as Low as $338

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Cheap Flights to St. Charles

Fall in love at first flight with your vacation to St. Charles by saving a ton of cash on your last-minute cheap flight. There’s no more scouring the internet for a good deal—book your flight to St. Charles on Hotwire, and you’ll be up, up, and on a getaway in no time.

Because once the wheels are down in St. Charles, the good times start rolling. So buckle up, you’re in for a fun ride.

Just the right flight

Don’t waste your time on endless searches for cheap airline tickets oneway or roundtrip. We’ll have you on your way to St. Charles with a tiny bag of pretzels in your hand before you can say “tray tables in the upright position”—and for a ticket price that works for your vacay budget.

So all you have to worry about is where you’re headed after the RST airport.

Frequently Asked Questions About flights to St. Charles

What is the cheapest month to fly to St. Charles?

Airline ticket prices fluctuate all the time, depending on the day of the week or the month of the year. The cheapest round trip flights to St. Charles are in April, but when you book your flight on Hotwire, savings are always in season.

How many airlines fly to St. Charles?

Variety is the spice of life, even when it comes to booking your next trip. Want options for airlines? You’ll find 16 to choose from for your flight to St. Charles.

What airport is best to fly into St. Charles?

When you’re planning your trip to St. Charles, convenience is the name of the game. Luckily, St. Charles Rochester Intl. Airport is nearby so you can deplane and get going on checking off everything on your St. Charles must-do list.

How much are flights to St. Charles?

Got very cheap flights on your vacation itinerary? When you book your airline tickets to St. Charles on Hotwire, you may just get what’s on your getaway wish list. With tickets as low as $338, you’ll have leftover cash for at least a magazine and a bottle of water at the airport book store.

How to get cheap flights to St. Charles?

The trick to saving a stack of cash on your flight to St. Charles? Snatch up that Hotwire flight deal when you see a killer rate because it could be gone in a flash. And with flights as low as $338 right now, why wait?

Can I fly to St. Charles right now?

With recent COVID-19 closures and reopenings, many people are wondering, “Is it safe to travel to  right now?” When it’s time to book your flight, be sure to check out the most up-to-date information on all safety measures, any restrictions, and guidance on traveling during the coronavirus pandemic.

St. Charles Flight Information
Destination airport
Rochester Intl.
Destination airport IATA code
RST
Roundtrip price
$338

Last Minute Hotel Deals in St. Charles

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3 out of 5
4353 Canal Pl SE, Rochester, MN
The price is $80 per night from May 19 to May 20
$80
per night
May 19 - May 20
Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (1,002 reviews)
No ice!
"We had appointments at the Mayo Clinic do needed to check in early and they made that happen so that was great . Only draw back was ice machines weren’t working on any of the floors ! Front desk person said they would go get some but when we went back at 7 we stopped and asked snd Ge said they didn’t ..."

Reviewed on Apr 12, 2024

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Kahler Grand Hotel
Kahler Grand Hotel
3 out of 5
20 2nd Ave Sw, Rochester, MN
The price is $149 per night from Apr 21 to Apr 22
$149
per night
Apr 21 - Apr 22
Stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 3 restaurants, and breakfast. Our guests praise the helpful staff and the clean rooms in ...
8.2/10 Very Good! (1,003 reviews)
"Construction. Which I know is unavoidable"

Reviewed on Apr 12, 2024

Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
3.5 out of 5
9 3rd Ave Nw, Rochester, MN
The price is $129 per night from Apr 21 to Apr 22
$129
per night
Apr 21 - Apr 22
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free WiFi, a fitness center, and onsite parking. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,179 reviews)
"In town a couple of days for a medical procedure. Had a jr suite which was very clean and comfortable. The beds were very comfortable, slept good both nights."

Reviewed on Apr 16, 2024

Kahler Inn and Suites - Mayo Clinic Area
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
4 out of 5
101 11TH Avenue SW, Suite A, Rochester, MN
The price is $120 per night from Apr 22 to Apr 23
$120
per night
Apr 22 - Apr 23
Stay at this 4-star business-friendly hotel in Rochester. Enjoy free WiFi, breakfast, and a free area shuttle. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (548 reviews)
"Nice place"

Reviewed on Apr 17, 2024

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
3.5 out of 5
110 Civic Center Drive NW, Rochester, MN
The price is $111 per night from Apr 28 to Apr 29
$111
per night
Apr 28 - Apr 29
Stay at this 3.5-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and a free area shuttle. Our guests praise the breakfast and the ...
9/10 Wonderful! (524 reviews)
"The property was near the clinic. The food choices in the immediate area were many and varied."

Reviewed on Apr 17, 2024

Hyatt House Rochester/Mayo Clinic Area
Hampton Inn Rochester-South
Hampton Inn Rochester-South
2.5 out of 5
1755 S Broadway, Rochester, MN
The price is $104 per night from May 5 to May 6
$104
per night
May 5 - May 6
Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (1,004 reviews)
"Good service"

Reviewed on Apr 17, 2024

Hampton Inn Rochester-South
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
3.5 out of 5
220 S Broadway, Rochester, MN
The price is $115 per night from Apr 28 to Apr 29
$115
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast. Our guests praise the restaurant and the helpful staff ...
8.8/10 Excellent! (519 reviews)
"Always our go-to in downtown Rochester. Clean, nice rooms. Affordable and well located. Good bar in the lobby and convenient parking. Will stay again!"

Reviewed on Apr 19, 2024

Hotel Indigo Rochester – Mayo Clinic Area, an IHG Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
AmericInn by Wyndham Rochester Near Mayo Clinic
3 out of 5
1625 Broadway Ave S, Rochester, MN
The price is $82 per night from Apr 28 to Apr 29
$82
per night
Apr 28 - Apr 29
Stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
7.8/10 Good! (250 reviews)
"I had a very nice stay. Loved the restaurant and comedy club. The room was on the smaller side but very clean. The pool/ hot tub area was clean. The only issue was the hot tub, the bubbler would run for a few minutes then shut off for 5-10 mins. Then run for 5 mins and shut off again. Other then ..."

Reviewed on Apr 15, 2024

AmericInn by Wyndham Rochester Near Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.