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Panama from $319

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Cheap round-trip flights to Panama

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

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Flights to Panama starting at $319

Have you been telling yourself, “2024 is the year I travel more and sit less”? Well, here we are and there you are. So, where are you going? Looks like a flight to Panama is calling. Good thing we can help you bag that flight out of town for cheap, so you can get your resolutions resolved.

Travel like you mean it

When you land it’s not straight to the tourist traps for you. You have things to do and see in Panama that aren’t on a map or in the “Best of. . .” guides. You know this region is filled with hidden haunts, locals-only know favorites, and the off-beat-so-weird-it’s-amazing places. And you plan to find every last one of them. Good thing you’ll save a grip of cash on your flight so you can daytrip far and wide.

You won’t have to wing it

So how do you score that killer deal on a flight to Panama? Easy, go through us. These aren’t pie in the sky deals, but ones you can actually score. Filter flights to Panama by:

  • Hotwire Hot Rate: Do you have a flexible schedule? Hit up the Hotwire Hot Rate and land a super cheap flight to Panama. We’ll reveal the airline and exact time after you book.
  • Price: How low can we go? Find out. We have prices from $319 to $660.
  • Duration: Want to get to Panama as fast as you can? Or maybe you don’t mind taking your time to save a few bucks here and there.
  • Departure or Arrival: Like to arrive in the a.m. to get your day going? Or are you a night owl that knows the best fun happens late night? The choice is yours.

So are you going to live up to those travel plans or kick the can to next year? Book your flight to Panama today and get going.

Last Minute Hotel Deals in Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is $115 per night from Apr 16 to Apr 17
$115
per night
Apr 16 - Apr 17
Stay at this 5-star luxury hotel in Panama City. Enjoy free WiFi, 3 restaurants, and a fitness center. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (2,124 reviews)
"Staff was very helpful in every way. They gave directions, changed money, supplied extra towels"

Reviewed on Mar 15, 2024

Hotel Riu Plaza Panama
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is $232 per night from Apr 1 to Apr 2
$232
per night
Apr 1 - Apr 2
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in ...
7.4/10 Good! (924 reviews)
"It was clean and beautiful. Staff was pleasant. Room was cleaned and mopped everyday. Overall a wonderful experience."

Reviewed on Mar 4, 2024

Dreams Playa Bonita Panama - All Inclusive
Crowne Plaza Panama Airport, an IHG Hotel

Crowne Plaza Panama Airport, an IHG Hotel

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is $120 per night from Mar 24 to Mar 25
$120
per night
Mar 24 - Mar 25
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, free parking, and breakfast. Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,753 reviews)
"Nice overnight hotel with clean rooms, friendly staff. Easy to get to from airport."

Reviewed on Mar 16, 2024

Crowne Plaza Panama Airport, an IHG Hotel
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Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
The price is $144 per night from Mar 25 to Mar 26
$144
per night
Mar 25 - Mar 26
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8/10 Very Good! (306 reviews)
Top hotel
"Top experience, very good."

Reviewed on Mar 15, 2024

Megapolis Hotel Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.